1. Sasaki Y, Hisatsune C, Ogawa Y, Yasui M, Mikoshiba K, Tsubota K. Deficiency of stimulated tear secretion in IP3 Receptor Types 2 and 3 knockout mouse

American Society of Cataract & Refractive Surgery 2007 Symposium & Congress. San Diego, April 27-May 2, 2007

1. Yamaguchi T, Negishi K, Kato N, Arai H, Toda I, Tsubota K. Factors Affecting Visual Function after Implantation of Artisan Phakic Intraocular Lens for High Myopia

The American Society of Cataract and Refractive Surgery (ASCRS) and the Japanese Society of Cataract and Refractive Surgery (JSCRS), ASCRS Symposium on Cataract and Refractive Surgery. San Diego, April 30, 2007

1. Shimmura S. Corneal Opacity and Cataract Surgery. Joint Symposium

The Association for Research in Vision and Ophthalmology (ARVO), Annual meeting, Florida, U.S.A. May 5-9, 2007  

1. Almulki L, Noda K, Amini R, Schering A, Miyahara S, Nakazawa T, Thomas KL, Miller JW, Gragoudas ES, Hafezi-Moghadam A. P-selectin glycoprotein ligand-1 blockade suppresses endotoxin-induced uveitis.
2. Dogru M, Wang Y, Hu Y, Okada N, Igarashi A, Fukagawa K, Shimazaki J, Tsubota K, Fujishima H. Tear Function and Ocular Surface MUC5AC, MUC16 mRNA Alterations in Patients With Atopic Keratoconjunctivitis.
3. Fujishima H, Takano Y, Murat D, Tanaka M, Okada N, Igarashi A, Tsubota K, Fukagawa K. 0.1% Cyclosporine Eye Drops for Patients With Vernal Keratoconjunctivitis.
4. Fukagawa K, Okada N, Igarashi A, Satake Y, Takano Y , Dogru M, Tanaka M, Kato N, Tsubota K, Fujishima H. Omega- 3 Polyunsaturated Fatty Acids ( PUFA ) Suppressed Stat - 6 Phosphorylation in Cultured Human Conjunctival Fibroblasts.
5. Hara S, Dogru M, Kawakita T, Kojima T, Matsumoto Y, Shimazaki J, Tsubota K. The Relation of Tear Function and Visual Out-come following Keratoplasty for Keratoconus
6. Higa K, Shimmura S, Miyashita H, Kawakita T, Shimazaki J, Tsubota K. N-cadherin expression in cultivated limbal epithelial cell colonies.
7. Higuchi A, Okubo Y, Tsubota K. Selenoprotein is a New Candidate for the Treatment of Dry Eye.
8. Igarashi A, Okada N, Satake Y, Dogru M, Fukagawa K, Shimazaki J, Tsubota K, Fujishima H. The Change of Prostaglandins, and Cysteinyl-leukotriene Concentrations in the Tears of Patients With Severe Allergic Conjunctivitis.
9. Imamura Y, Hashizume K, Hirasawa M, Noda S, Shimizu T, Shirasawa T, Shinoda K, Miyake Y, Tsubota K. Retinal Degeneration in SOD1-deficient Mice: Electrophysiology and Histopathology.
10. Imamura Y, Hirasawa M, Hashizume K, Noda S, Shirasawa T, Shinoda K, Miyake Y, Tsubota K. Characterization of Retinal
    Degeneration in SOD1 - Deficient Mice: Electrophysiology and Histopathology.
11. Izumi-Nagai K, Nagai N, Satofuka S, Koto T, Mochimaru H, Tsubota K, Ohgami K, Ohno S, Ishida S. Lutein Inhibits Choroidal Neovascularization in Mice.
12. Kato N, Shimmura S, Kawakita T, Miyashita H, Higa K, Yoshida S, Ogawa Y, Okano H, Tsubota K. Epithelial-mesenchymal tran-sition in the pathogenesis of pterygium.
13. Kawakita T, Shimmura S, Tsubota K, Shimazaki J, Tseng SCG. Cellular senescence due to epithelial mesenchymal transition during clonal expansion of murine limbal epithelial cells.
14. Kawashima M, Kawakita T, Shimmura S, Higa K, Shimazaki J, Tsubota K. Caracterization of Human Limbal Melanocytes Expanded in vitro.
15. Koto T, Nagai N, Mochimaru H, Izumi-Nagai K, Satofuka S, Shinoda H, Noda K, Kurihara T, Ozawa Y, Inoue M, Tsubota K, Ishida S. Anti-inflammatory effect of eicosapentaenoic acid on diabetic retina in vivo and cytokine expression in vitro.
16. Kumagai Y, Kurokawa M.S, Ueno H, Kayama M, Tsubota K, Nakatsuji N, Nito S, Ueno S, Suzuki N. Induction of Corneal Epithelium - Like Cells From Cynomorgus Monkey Embrionic Stem Cells and Their Experimental Transplantation to Damaged Cornea.
17. Kurihara T, Ozawa Y Nagai N, Inoue M, Oike Y, Okano H, Tsubota K, Ishida S. Neuroprotective Effects of Angiotensin II Type 1 (AT1R) Receptor Blocker Telmisartan on Early Diabetic Retina.
18. Miyashita H, Higa K, Kato N, Goda N, Tsubota K, Shimmura S. Hypoxia increases the colony forming efficiency and inhibited the differentiation of human limbal epithelial cells.
19. Mochimaru H, Nagai N, Hasegawa G, Kudo-Saito C, Yaguchi T, Satofuka S, Ozawa Y, Tsubota K, Kawakami Y, Ishida S. Immunization of mice with dendritic cells primed with epitope peptide derived from VEGF receptor 2 supresses choroidal neovascularization.
20. Nagai N, Oike Y, Izumi-Nagai K, Koto K, Satofuka S, Shinoda S, Ozawa Y, Inoue M, Tsubota K, Ishida S. Suppression of choroidal neovascularization by inhibiting angiotensin-converting enzyme: minimal role of bradykinin.
21. Nakamura S, Shibuya M, Nakashima H, Tsubota K. Effect of Duration of Blink Suppression on the Corneal Epithelial Disorder in a Rat Blink Suppressed Dry Eye Model.
22. Nakao S, Noda K, Almulki L, Hisatomi T, Thomas KL, Miller JW, Gragoudas ES, Hafezi-Moghadam A. Enhanced age-related corneal angiogenesis in apolipoprotein E-deficient mice.
23. Negishi K, Kumanomiodo T, Utsumi Y, Tsubota K. The effect of higher order aberrations on visual function in keratoconic eyes with a hard contact lens.
24. Noda K, Miyahara S, Nakazawa T, Hisatomi T, Almulki L, She H, Nakao S, Miller JW, Gragoudas ES, Hafezi-Moghadam A. Blockade of vascular adhesion protein-1 suppresses endotoxin-induced uveitis.
25. Noda T, Fujiike K, Ohno K, Negishi K, Ohnuma K. Evaluation of Visual Function in Eyes With Cataract Using a Point Spread Function Analyzer.
26. Ogawa J, Ogawa Y, Dogru M, Fujishima H, Matsumoto H, Tsubota K. Therapeutic Applications of Soft Contact Lenses in Severe・Dry Eye With Chronic Graft-versus- Host Disease.
27. Ogawa Y, Shimmura S, Kawakita T, Kato N, Miyashita H, Yoshida H, Tsubota K. Collagen Secretion From HSP 47-Expressing Conjunctival Basal Epithelia in Dry Eye Associated With Chronic Graft versus Host Disease.
28. Omoto M, Shimmura S, Yoshida S, Miyashita H, Tsubota K. Corneal wound healing following penetrating keratoplasty on mice.
29. Ozawa Y, Nakao K, Shimazaki T, Shimmura S, Kurihara T, Ishida S, Yoshimura A , Tsubota K, Okano H. SOCS3 is required to temporally fine-tune photoreceptor cell differentiation.
30. Satofuka S. Ichihara A, Nagai N, Koto T, Shinoda H, Ozawa Y, Tsubota K, Itoh H, Oike Y, Ishida S. Nonproteolytically activated prorenin promotes pathologic, but not physiologic, retinal neovascularization.
31. Shimazaki J, Uchino Y, Tsubota K. Late Irreversible Corneal Edema After Laser Iridotomy.
32. Shimmura S, Miyashita H, Kawakita T, Goda N, Suematsu M, Tsubota K. Metabolomic analysis of calcium-induced differentiation of murine corneal epithelial cell progenitors.
33. Tanaka M, Dogru M, Takano Y, Fukagawa K, Kato N, Satake Y, Tsubota K, Fujishima H. Relation of Pollenation and Out Patient Admission Patterns in Seasonal Allergic Patients.
34. Thomas KL, Noda K, Miyahara S, Nakazawa T, Hisatomi T, Miller JW, Gragoudas ES, Kawai Y, Mashima Y, Hafezi-Moghadam A. Expression of vascular adhesion protein-1 in ocular tissues of endotoxin-induced uveitis.
35. Tomita M, Shimmura S, Inokawa S, Kawashima M, Tsubota K, Shimazaki J. Astigmatism Following Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty.
36. Tsubota K, Mishima M, Inoue H, Yamada H, Saito I. Clusterin is the Lacrimal Gland Side Population Secretory Glycoprotein and Can RestoreLacrimal Gland Function Through Suppressing Reactive Oxygen Species; A Potential New Therapy for Age - Related Dry Eye Disorders.
37. Tsubota K. Clinical Trials.
38. Usui T, Sugisaki K, Yokoo S, Yamagami S, Amano S, Nagai N, Ishida S. Inhibition of corneal neovascularization by blocking the angiotensin II type 1 receptor.
39. Wakamatsu TH, Dogru M, Sasaki Y, Ward S, Imamura Y, Shimizu T, Shirasawa T, Shimazaki J, Tsubota K. Tear Functions in the Superoxide Dismutase - 1 Deficient ( SOD - 1 - / - ) Mice: An Animal Model for Dry Eye.
40. Wang Y, Ogawa Y, Dogru M, Tatematsu Y, Uchino M, Okamoto S,・Tsubota K. Characteristics of the Tear Functions and Ocular Surface・in Patients With Chronic Graft-Versus-Host Disease Related Dry Eye・Disease.
41. Ward S, Dogru M,.Wang Y, Hu Y,. Wakamatsu T.H, Igarashi A, Inoue H, Saito I, Tsubota K. The Acute Effects of Passive Smoke Exposure on the Ocular Surface and Tear Stability of Contact Lens Wearers.

American Aging Association Annual Meeting

1. Wakamatsu TH, Dogru M, Sasaki Y, Ward S, Imamura Y, Ogawa Y, Shimizu T, Shirasawa T, Shimazaki J, Tsubota K. Comparison of tear functions in senescent Cu, Zn Superoxide Dismutase-1 (SOD-1)-Knock-out mice with the wild type SOD(+/+) mice.

International Ocular Surface Society, Fort Lauderdale, USA May 10-11, 2007

1. Dogru M. The Impact of Nasal Conjunctivochalasis on Tear Functions and Ocular Surface.

12th Congress of the International Association of Biomedical Gerontology, Spetses, Greece, May 20-24, 2007

1. Tsubota K, ・Mishima K, Obara K, Yamada H, Inoue H, Saito I. Reactive oxygen species can be controlled by the secretory glycoprotein, clusterin, from side population cells in the lacrimal gland: a new intervention for age-related dry eye disorders.

American Aging Assciation Annual Meeting, San Antonio, USA June 1-5, 2007

1. Kawakita T, Shimmura S, Shimazaki J, Tsubota K, Tseng SCG. Epithelial mesenchymal transition by Cellular Senescence.

13th International Congress of Mucosal Immunology (ICMI)　Tokyo July 9-12, 2007

1. Dogru M, Wang Y, Hu Y, Ward S, Imamura Y, Inoue H, Saito I, Tsubota K．The effects of acute passive cigarette smoke exposure on the tear film and ocular surface of healthy non-smoker subjects.
2. Ogawa Y, Shimmura S, Kawakita T, Kato N, Miyashita H, Yoshida S, Tsubota K. Collagen Secretion from HSP 47-Expressing Conjunctival Basal Epithelia in Dry Eye Associated with Chronic Graft versus Host Disease.

The 5th International Conference of Aquaporin Nara, July 13-16, 2007

1. Sasaki Y, Kawedia JD, Menon AG, Yasui M, Tsubota K. The Difference of Aquaporin 5 Distribution in Acinar and Ductal Cells in Lacrimal and Parotid Glands.

World Glaucoma Congress. Singapore, July 18-23, 2007

1. Shiba D, Oura A, Morifuji H, Yuki K, Nakada A, Yamaya T, Yoshida A, Kano K, Kuwayama Y. Comparison of intraocular pressure measurement by Goldmann applanation tonometer, ocular response analyzer, and dynamic contour tonometer.

5th International・Conference on the Tear Film & Ocular Surface: Basic Science and・Clinical Relevance. Taormina, Sicily, Italy September 5-8, 2007

1. Ban Y, Ogawa Y, Goto E, Uchino M, Terauchi N, Seki M, Nakaya M, Saeki M, Dogru M, Tsubota K. Tear function and lipid layer alterations・in chronic graft-versus-host disease.
2. Dogru M, Ibrahim O, Matsumoto Y, Takano Y, Tanaka M, Satake Y, Fukagawa K, Fujishima H, Tsubota K. Evaluation of Conjunctival Inflammatory Status by Confocal Laser Microscopy and Conjunctival Brush Cytology in Patients with Atopic Keratconjunctivitis (AKC).
3. Ogawa Y, Razzaque MS, Kameyama K, Hasegawa G, Shimmura S, Kawai M, Yamazaki K, Okamoto S, Ikeda Y, Tsubota K,
   Kawakamai Y, Kuwana M. Collagen secretion from HSP 47-expressing lacrimal gland myoepithelia in dry eye associated with chronic graft versus host disease.
4. Tsubota K, Mishima K, Obara K, Yamada H, Inoue H, Saito I. Reactive oxygen species can be controlled by the secretory glycoprotein, clusterin, from side population cells in the lacrimal gland: a new intervention for age-related dry eye disorders.
5. Uchino M, Ogawa Y, Uchino Y, Mori T, Okamoto S, Tsubota K. Dry eye・after hematopoieic stem cell transplantation.
6. Uchino Y, Uchino M, Dogru M, Fukagawa K, Shimmura S, Takebayashi T, Shaumberg D, Tsubota K. Prevalence of Dry Eye Syndorome among Japanese VDT Users.
7. Wakamatsu TH, Dogru M, Sasaki Y, Ward S, Imamura Y.・ Histopathological alterations in senescent Cu, Zn−superoxide・ dismutase-1 (SOD−1)−knock-out mice: A new model for dry eye.
8. Ward S, Dogru M, Wakamatsu T, Ibrahim O, Kaido M, Matsumoto Y, Yokoi N, Ueda M, Tsuyama A, Tsubota K. Implementation of a New Questionnaire into the Recently Revised Japanese Dry Eye Diagnostic Criteria.

Gordon Conference Aging of Biology, Les Diablerets, Switzerland, September 23-28, 2007

1. Kawakita T, Shimmura S, Shimazaki J, Tsubota K, Tseng SCG. Epithelial mesenchymal transition by Cellular Senescence.

American Academy of Ophthalmology, New Orleans, USA, November 10-13, 2007

1. Tsubota K, Goto E, Dogru M, Tseng S. Instruction Course: New strategy for the management of dry eye syndromet.
2. Tsubota K. Introduction Dogru M. Clinical Pearls in the Diagnosis and Management of Tear Stability and Visual Function.